From my experience, etsy.com is more well known than artfire.com yet the people that know of artfire.com seem to like it more. I sell on both, being on etsy.com longer though. I've had a couple of sales but that was over a span of a couple of years, nothing to brag about. I haven't had a sale on artfire.com but within the year I've joined, I've had more inquiries for custom orders from it.
I think because etsy.com is widely known, I know more artists that use it and some have done very well on it while others, such as myself, do not get many sales. I don't have many items listed on etsy.com or artfire.com due to the fact that I don't have good way of taking quality photos of my work but I'm hoping that will change when I get a light box going. Another site that I've posted on is craftgawker.com but I don't know how many hits I get on there. I also have this blog and a Facebook fan page but I don't seem to be gaining a strong fan base. Gotta keep working on getting exposure, I guess!
